Thursday, December 28, 2006
The government has decided that food from cloned animals is safe to eat and does not require special labeling.
The Food and Drug Administration planned to brief industry groups in advance of an announcement Thursday morning. The FDA indicated it would approve cloned livestock in a scientific journal article published online earlier this month.
Consumer groups say labels are a must, because surveys have shown people to be uncomfortable with the idea of cloned livestock.
However, FDA concluded that cloned animals are "virtually indistinguishable" from conventional livestock and that no identification is needed to judge their safety for the food supply...but critics of cloning say the verdict is still out on the safety of food from cloned animals.
"Consumers are going to be having a product that has potential safety issues and has a whole load of ethical issues tied to it, without any labeling," said Joseph Mendelson, legal director of the Center for Food Safety.
For the whole story, click here.
The babies who are murdered to order
By Matthew Hill
The plastic bag looks as if it contains meat. But then a right leg is taken from it and placed surgically on the morgue table, followed by the left one. Then the torso. The head follows, a gaping cavity where the brain used to be.
But it is only when the gloved hand of the pathologist examines the tiny fingers of a baby aged about 30 weeks that the full horror of what I am witnessing sinks in.
This shocking scene was captured on video at post-mortem examinations carried out on behalf of Ukrainian mothers who claim their babies were stolen from them at birth.
The film was shown to me by an incredibly brave charity worker called Tatyana Zhakarova, who represents up to 300 families who believe their healthy babies were deliberately targeted at a maternity hospital in the Ukraine's most easterly city of Kharkiv.
The babies, believes Tatyana, were taken at birth to have their organs and stem cells harvested as part of a sickening but highly lucrative international trade.
For the rest of article, click here.
As Minds Age, What’s Next? Brain Calisthenics
By PAM BELLUCK
PROVIDENCE, R.I. — Is there hope for your hippocampus, a new lease for your temporal lobe?
Science is not sure yet, but across the country, brain health programs are springing up, offering the possibility of a cognitive fountain of youth.
From “brain gyms” on the Internet to “brain-healthy” foods and activities at assisted living centers, the programs are aimed at baby boomers anxious about entering their golden years and at their parents trying to stave off memory loss or dementia.
“This is going to be one of the hottest topics in the next five years — it’s going to be huge,” said Nancy Ceridwyn, co-director of special projects for the American Society on Aging. “The challenge we have is it’s going to be a lot like the anti-aging industry: how much science is there behind this?”
Dozens of studies are under way. Organizations like AARP are offering tips on brain health. And the Alzheimer’s Association conducts hundreds of Maintain Your Brain workshops, many at corporations like Apple Computer and Lockheed Martin. To read on, click here.
Interesting related links: Happy Neuron.com and MyBrainTrainer.com.
Saturday, December 23, 2006
[Hat tip to R. Alta Charo for this Christmas gift] -- I know this bit of info will make my Christmas cheerier! And very Happy Holidays for the rest of our readers!
From Health magazine this month:
Listen to the way people malign chocolate: Sinful! Decadent! To die for! There’s even that popular restaurant dessert known as “Death by Chocolate.” But is this any way to talk about a loved one—especially during the season of comfort and joy? Not at Health. With evidence mounting that some kinds of chocolate are actually good for you, we come bearing gifts: six delicious reasons why you should nurture a chocolate habit (within reason) and taste-tested advice on what to try. Merry munching:
1. A happier heart
Scientists at the Harvard University School of Public Health recently examined 136 studies on cocoa—the foundation for chocolate—and found it does seem to boost heart health, according to an article in the European journal Nutrition and Metabolism.
“Studies have shown heart benefits from increased blood flow, less platelet stickiness and clotting, and improved bad cholesterol,” says Mary B. Engler, PhD, a chocolate researcher and director of the Cardiovascular and Genomics Graduate Program at the University of California, San Francisco, School of Nursing. These benefits are the result of cocoa’s antioxidant chemicals known as flavonoids, which seem to prevent both cell damage and inflammation.
2. Better blood pressure
If yours is high, chocolate may help. Jeffrey Blumberg, PhD, director of the Antioxidants Research Laboratory at Tufts University, recently found that hypertensive people who ate 3.5 ounces of dark chocolate per day for 2 weeks saw their blood pressure drop significantly, according to an article in the journal Hypertension. Their bad cholesterol dropped, too. People who ate the same amount of white chocolate? Nothing. (It doesn’t have any cocoa—or flavonoids.) Word to the wise: 3.5 ounces is roughly equal to a big bar of baking chocolate, so the participants had to cut about 400 calories out of their daily diets to make room. But you probably don’t have to go to those lengths. Just a bite may do you good, Blumberg says.
3. Muscle magic
Chocolate milk may help you recover after a hard workout. In a small study at Indiana University, elite cyclists who drank chocolate milk between workouts scored better on fatigue and endurance tests than those who had some sports drinks. Yoo-hoo!
4. TLC for your skin
German researchers gave 24 women a half-cup of special extra-flavonoid-enriched cocoa every day. After 3 months, the women’s skin was moister, smoother, and less scaly and red when exposed to ultraviolet light. The researchers think the flavonoids, which absorb UV light, help protect and increase blood flow to the skin, improving its appearance.
5. Brain gains
It sounds almost too good to be true, but preliminary research at West Virginia’s Wheeling Jesuit University suggests chocolate may boost your memory, attention span, reaction time, and problem-solving skills by increasing blood flow to the brain. Chocolate companies found comparable gains in similar research on healthy young women and on elderly people.
6. Good loving (maybe)
Italian researchers wanted to know whether chocolate truly is an aphrodisiac. In a survey of 143 women published in the Journal of Sexual Medicine, those who ate chocolate every day seemed to have more sex drive, better lubrication, and an easier time reaching orgasm. Pass the Godiva, right? Not so fast. The women who ate chocolate were all younger than the ones who didn’t; it was age and not chocolate that made the difference. Still, if a double-chocolate raspberry truffle puts you in the mood, why let science get in the way?
Tuesday, December 19, 2006
Monday, December 18, 2006
Sara Lincoln suffers when she hears her adopted child cry. The baby was born addicted to crack cocaine because the child's birth mother used the drug while pregnant. Now Lincoln plans to adopt another child soon to be born to the same woman. The child will also be a crack baby. While Lincoln and her husband work to terminate the birth mother's parental rights, the children caught in the middle suffer the symptoms of being born addicted to drugs. Lincoln decided that the best thing to do is start a Connecticut chapter of Project Prevention, a controversial group that pays drug addicts up to $300 to use longterm birth control or get sterilized. Project Prevention has touched off an ethical firestorm everywhere it's gone, and Connecticut should prove no different.
The claim is that Project Prevention is unethical because it too close to eugenics, that it coerces addicts into giving up their reproductive choices because of an undue financial incentive, that it is paternalistic. But I'm having a hard time buying into these arguments, especially since there doesn't seem to be qualitative or quantative data that the addicts who sign up for this program (Barbara Harris said Project Prevention has served nearly 2,000 "clients." ) have regretted their actions. Does these women feel coerced? Or do they feel a sense of relief? And what of the ethics of public health, that we all pay when our children suffer?
[Last Thursday] came the news of a precipitous drop in the breast cancer rate in the U.S. Todd Ackerman, one of the Houston Chronicle's fine medical journalists, reports: The most significant decline ever recorded in U.S. breast cancer rates may have been the result of millions of older women stopping hormone replacement therapy, according to a new analysis.
Researchers at the University of Texas M.D. Anderson Cancer Center revealed Thursday that the rate dropped 7 percent in 2003 and suggested a striking reason: women's abandonment of menopause hormones after a large study was stopped the year before because the pills were increasing health risks.
To be frank, this makes me feel a bit like Marvin the Martian (.wav file), and it has everything to do with evidence-based medicine. EBM, as it is often called, is roughly defined as "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patient."
My own reaction, as well as a common reaction of laypersons when they hear this definition, was something along the lines of, 'What do you mean? What else have physicians been doing?' I have personally been writing and thinking a great deal about EBM in the last month, and …I will not, therefore, go into too much detail about the controversy over EBM, but suffice it to say that while I think that awareness of some of the practical problems and pitfalls of EBM is merited, I also think such problems do not negate the conceptual importance of EBM, and that avoiding any commitment to engage the problems of EBM can result in dire consequences.
Jay Katz documents some of these consequences in the course of breast cancer treatment in the 20th century, but the saga of hormone replacement therapy ("HRT") is another sad piece of the puzzle. From my own research, I found that in 2000, physicians issued over 45 million prescriptions for the most common HRT, in the staunch belief that HRT would help prevent a range of diseases for postmenopausal women (including cancer and coronary disease).
Such beliefs -- in terms of outcomes and efficacy -- had not been confirmed via rigorous scientific studies. When such a study was finally done by the Women's Health Initiative, the "unexpected" findings were that HRT actually seemed to increase the risk of certain kinds of invasive breast cancers. In fact, the study was halted on the recommendation of the data safety and monitoring board because it appeared to be doing more harm than good.
Thus, providers had issued prescriptions for HRT for millions of women in the belief that it might help reduce the risk of certain kinds of cancer, which belief had simply not been confirmed by the best kinds of evidence (which are not randomized controlled trials in every instance).
And now we hear the news that the most plausible single factor explaining the highly statistically significant drop of 7% in the 2003 U.S. breast cancer rate is the fact that providers ceased writing the prescriptions and women stopped taking them.
Please do not misunderstand this post as an attack on physicians or providers.
I both understand and agree that there is immense value to a physician's practical experience, training, and intuition. But I think that such sources of knowledge, unaccompanied by the best evidence (quantitative and qualitative) can be exceedingly dangerous when used as the sole criteria for assessment of an intervention. Often, there is simply no way to know if a given intervention will be therapeutic or not. It's not the uncertainty that is the problem, IMO; it's the willingness to plow ahead, to avoid incorporating that uncertainty into clinical practice, that concerns me.
Anyway, I obviously have a great deal more to say about this topic in general, and what I have said here about EBM is merely the tip of a very important iceberg. But I do think the news about HRT is an important theme in the overall discourse, and I wanted to mention it.(You can find a short piece I wrote on EBM and the recent news involving stents here (.pdf), and you can find an article on another sad chapter in the breast cancer saga here, which I wrote before I had ever heard of EBM, but which fits in pretty obviously with some of the points I am concerned with here).
I can also recommend some excellent sources on ethics, policy, and EBM, so if anyone is interested please feel free to email me. email@example.com
Sunday, December 17, 2006
....I was angry at the idea that where donor conception is concerned, everyone focuses on the "parents" -- the adults who can make choices about their own lives. The recipient gets sympathy for wanting to have a child. The donor gets a guarantee of anonymity and absolution from any responsibility for the offspring of his "donation." As long as these adults are happy, then donor conception is a success, right?
Not so. The children born of these transactions are people, too. Those of us in the first documented generation of donor babies -- conceived in the late 1980s and early '90s, when sperm banks became more common and donor insemination began to flourish -- are coming of age, and we have something to say...
For the whole article, click here.
More from the Washington Post article here.
Most embryos will never develop into babies because the defects make it impossible for them to survive when they are implanted back into the womb. But the discovery explains why so many fertility treatments fail, with thousands of women going through several expensive and painful cycles of treatment in the hope of having a child. It will add to worries that some genetic changes may occur in the children which are not yet being picked up by doctors.
For more, click here.
Thursday, December 14, 2006
The announcement was made by officials of the National Institutes of Health as they halted two clinical trials, in Kenya and Uganda, on the ground that not offering circumcision to all the men taking part would be unethical. The success of the trials confirmed a study done last year in South Africa.
AIDS experts immediately hailed the finding...Uncircumcised men are thought to be more susceptible because the underside of the foreskin is rich in Langerhans cells, sentinel cells of the immune system, which attach easily to the human immunodeficiency virus, which causes AIDS. The foreskin also often suffers small tears during intercourse. But experts also cautioned that circumcision is no cure-all. It only lessens the chances that a man will catch the virus; it is expensive compared to condoms, abstinence or other methods; and the surgery has serious risks if performed by folk healers using dirty blades, as often happens in rural Africa. To read on, click here.
Monday, December 11, 2006
- A new shot in the arm against cancer. The newly approved HPV vaccine represents a different approach to fighting cancer. Instead of just screening patients to spot cancer early, doctors can use this vaccine to actively prevent it.
- Trans is fat non grata. This year it became easier to avoid trans fats after the FDA required food manufacturers to list trans fat content in the Nutrition Facts portion of food labels, the first major change to the label in over a decade..
figured it out? Massachusetts adopted the most promising plan yet for universal health insurance coverage. Massachusetts
- New treatment for macular degeneration. A promising new approach focuses on angiogenesis, or the formation of blood vessels. The FDA approved Lucentis, an anti-angiogenic drug aimed at the blood vessels that cause wet macular degeneration, a leading cause of blindness.
- Germ warfare—and the germs are winning some battles. Antibiotic-resistant “superbugs” are causing more trouble than ever. Virulent strains of bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile, once seen only in hospital settings, are now circulating in communities.
- Vaccines, kid stuff no more. “Getting your shots” is becoming a bigger part of adult preventive medicine. In 2006, the FDA approved Zostavax, the first vaccine against shingles, a condition that typically affects people over age 60.
- Drug approvals—with strings attached. The FDA allowed the multiple sclerosis drug Tysabri back on the market, with careful restrictions to ensure patients are closely monitored.
- Bird flu preparations: Don’t chicken out now. The disease continues to smolder, vaccine development inches forward, and the public and the press are showing signs of bird flu fatigue. Still, preparation is time and money well spent, because a pandemic could be horrific.
- Calls for FDA reform getting louder and clearer. The
released a report calling for two dozen reforms. One major theme: The approval process will never ferret out all the problems with a drug, so the agency needs tough, new powers to better monitor drugs after they are on the market. Instituteof Medicine
- D: Finally, a vitamin makes the grade. Several new studies suggest that the so-called sunshine vitamin (because it’s produced in skin exposed to sunlight) may protect against cancer.
Friday, December 08, 2006
While reading the article I was struck by obvious ethical conflicts. The first is the principle of non-malificence, or a doctor’s obligation to do no harm. Is intentionally creating a child with a significant physical disability violating this principle? Yes. The individuals involved would be writing the child’s life story for them, and setting them up for a life of pain and struggling. The article quotes Dr. Robert J. Stillman who reminds us all that “one of the prime dictates of parenting is to make a better world for our children.” One cannot forget the responsibility of the parent and their obligation to do what is in the best interest of their child. Is the “deliberate crippling” of these children the way to do that? I say no.
The second major issue that stuck out to me was the idea of the child’s rights. A lesbian couple, both of which are deaf, was referred to in the article. They decided that the best child for them would be a child with deafness, so they searched for a deaf sperm donor to increase their chances. They were successful and their son was born mostly deaf. They then selected to not give him hearing aids. This is absurd! They are denying their child the right to hear. They have withheld opportunity and ability. The medical community or social society should not support such behavior. The precedent being set by such actions is very dangerous.
Numerous case examples brought up in the article were scenarios of parents choosing a dwarfism gene, and saying that having a child with dwarfism, like themselves, would be “a blessing” and they could not imagine what life would be like if their average height child had to deal with little parents. But I think that the meaning of that claim is coming from a different place. I think that what many parents are probably thinking is “what is my life going to be like when she is different from me?”
I have a strong belief that much of the use of the new reproductive technology comes from a selfish place in parents. The title of this article is pitch-perfect, “Wanting Babies Like Themselves…” In choosing genetic defects for their children, parents are manipulating the PGD process and taking the preventative intention out of this technology. As Dr. Yury Verlinsky states, “If we make a diagnostic tool, the purpose is to avoid disease.” People need to be cautious to not take advantage of biotechnology, take care in their decision-making, and beware of shortsightedness.[written by kmcmanamy, a University of Vermont student -- thanks, Casey!]
Thursday, December 07, 2006
Seselj is being held on charges of conspiratorial acts promoting ethnic cleansing and the expulsion of all non-Serbian peoples from the Balkan territories under their control in the early 1990’s.
The spokesman for the UN War Crimes Tribunal announced yesterday that there was “grave concern” for the health of the prisoner, and that if necessary, they were prepared to take steps in order to intervene.
A statement issued by the tribunal and quoted in BBC’s December 6th article, clarifies: "The trial chamber ordered the authorities of the Kingdom of the Netherlands to provide medical services - which may in the case of medical necessity include intervention such as drip-feeding - with the aim of protecting the health and welfare of the accused and avoiding loss of life." (http://news.bbc.co.uk/2/hi/europe/6214862.stm)
The issue, however, is a bit stickier than the statement seems to imply. Similar issues have been under public watch recently- in the case of prisoners at Guantanamo, the United Nations stood to uphold the rights of those on hunger strike, essentially proclaiming force-feeding unethical and a violation of international law. Further, if the hunger-striker is deemed able minded at the time of statement, he or she can refuse future medical treatment even it is the final avenue to saving his or her life.
This last bit is especially conspicuous here, as it has also been reported that just before Seselj’s transfer to a hospital Wednesday, he issued a handwritten statement explicitly rejecting all medical treatment.
Seselj’s supporters from the Serbian Radical Party (SRS), an organization he leads and to which he has recently been reelected in his absence, claim the tribunal is acting irresponsibly. One article quotes a spokesman for the SRS, “Seselj has grave kidney problems and we're seriously concerned for his life.” Among the party there is popular demand for the leader to be moved closer to home; to a hospital in Belgrade.
In 1991, the World Medical Association issued their “Declaration of Malta,” a detailed statement essentially banishing the practice of force-feeding under distinct circumstances. A link to the form can be found on Amnesty International’s website: http://web.amnesty.org/pages/health-ethicswmahs-eng
Essentially, the declaration puts the desire of the hunger-striker first, although in rather runny, ambiguous terms to my eye. One section of the preamble, however, does seem abundantly clear.
It states, “The ultimate decision on intervention or non-intervention should be left with the individual doctor without the intervention of third parties whose primary interest is not the patient's welfare. However, the doctor should clearly state to the patient whether or not he is able to accept the patient's decision to refuse treatment or, in case of coma, artificial feeding, thereby risking death. If the doctor cannot accept the patient's decision to refuse such aid, the patient would then be entitled to be attended by another physician.” (reference link above)
Without little relevant working knowledge of international law and the procedures recognized or followed by The Hague, I feel I can’t draw any definitive lines on the proper course to follow in the case of the striking Seselj, but am obliged to allow the referenced information speak for itself.
It will be interesting indeed to see what type of example The Hague chooses to set next.
Wednesday, December 06, 2006
Despite the intense gendered based caste discrimination, the Dalit women have collectively participated in resistance movements trying to change this unfair system and have been actively appealing for help from the international community. Several international treaties (ICCPR, ICESCR, ICERD and CEDAW) could be used in international bodies to persuade the South Asian governments to pass and enforce laws that protect Dalit women’s human rights and offer them equal rights with men. Furthermore, 180 countries accepted the Millennium Development Goals (MDG) and the removal of social inequalities (i.e. reduce poverty, offer access to education, ensure gender equality etc.) impacting Dalit women (which account for 2% of the world population) represents a necessary step towards the realization of these goals.
The discrimination against Dalit women is an issue that has been brought in front of international bodies as early as 1995, culminating with the drafting of the Hague Declaration on the Human Rights and Dignity of Dalit Women which occurred at the Hague Conference on Dalit Women's Rights, in November 2006. The Hague conference also resulted in several recommendations being made to the governments of India, Pakistan, Bangladesh and Sri Lanka to correct the injustices made towards Dalits. These measures were meant to counter the widespread discrimination and violence against Dalit women, not only by pressuring governments to pass the appropriate laws, but also making sure that these governments take all necessary measures to enforce the rules and protect the Dalit women’s basic human rights. There rights range from parliamentary representation, property rights, antidiscrimination, anti-violence rules, right to education and equal protection under the law. The goal of the Hague Conference was to involve international bodies (such as the UN, EU and other multi-national NGOs) to build support for Dalit women to achieve these basic rights by 2015. This was viewed as a necessary step in order to achieve the targets of the MDG and close the wide social gap for this discriminated group. Read more:
During the 19th century in South Africa a growing demand for labor occurred as a result of the discovery of diamonds and gold. A need for men to work the mines created a basis of cheap labor, where the worker's families would remain in rural areas and their wages were sent home. This was an appealing labor system for both the employers and the state. The long-term separation of migrant men from their wives and families, along with the ever-present dangers of mining work and other high-risk, low-paid jobs, helped foster aggressive masculinities and sexualities among migrant laborers. These in turn have contributed massively to the rapid spread of HIV/AIDS. Both the need for multiple partners and a desire for flesh-to-flesh contact played a massive role in the spread of HIV in South Africa. These actions were seen as a normal mechanism to cope with life on the mines. Another contributor to the HIV/AIDS epidemic was the prevalence of sexually transmitted infections. Syphilis was one STI which was found at a high rate in the urban and rural areas of black South Africa. Individuals infected with STIs are proven to be much more susceptible to HIV/AIDS contraction. While their husbands were off working on the mines, wives left at home were often forced to have relations with multiple sex partners in exchange for groceries and clothing. Another factor which contributed to the rise of this epidemic was homosexual relations between men on the mines. After the men had multiple sexual relations with urban women, many of them were getting sick, especially with syphilis. This led the men to perceive the urban women as 'unclean' and they began to satisfy their sexual needs with each other, as a safer alternative. Many miners were married to other men on the mines, proving that this was an ongoing issue. This cultural practice was seen as an attempt to curb the spread of STIs and HIV. These are just a few of the reasons why the mining of diamonds in South Africa, has contributed greatly to the huge epidemic of AIDS.
Sounds like another good reason to stick to cubic zirconia....
[Addendum December 8, 2006 -- the movie Blood Diamonds with Leonardo DiCaprio and Jennifer Connelly has just come out, providing yet more reasons to think twice about supporting an industry that, in the past, has contributed to miserable living conditions and has yet (as far as I know) to act on alleviating those conditions it helped set up.]
Tuesday, December 05, 2006
The Science and Health section of today's NYT has this article about a new use for PGD: parents--who may not be infertile--using the procedure to select "for" a particular condition. A new article in the journal Fertility & Sterility presents the first actual data I've heard about on this issue. According to a study performed by the Genetics and Public Policy Center at Johns Hopkins, 3% of infertility clinics surveyed reported that they had intentionally used PGD to identify and implant embryos with a particular disability. (In press: Baruch S, Kaufman D, Hudson KL. Genetic testing of embryos: practices and perspectives of US IVF clinics. Fertil Steril 2006)
A lot has been written about whether PGD (and prenatal testing) to avoid the birth of people with disabilities is ethical--eliminating the disability by eliminating embryos. Adrienne Asch and David Wasserman offer the best (to my mind) argument for this view in a book chapter called "Where Is the Sin in Synecdoche?" (chapter 7 in Quality of Life and Human Difference: Genetic Testing, Health Care, and Disability).
In the present case, however, the closest parallel I can think of in the bioethics literature is the controversy about whether it is morally acceptable for Deaf parents, who see deafness as a necessary ticket to enter the Deaf culture, to decide against cochlear implants for their children. You can read more here, here, here, and here.
Lots of important questions here about disability, about what parents owe their children, about what's best for children, and about parental rights and how much say society should have over these questions.
Sunday, December 03, 2006
Palliative sedation is the use of sedative medications to relieve extreme suffering that cannot be diminished with any other form of medication or treatment. These symptoms are also known as refractory symptoms. Palliative sedation puts people in an unconscious state while the disease takes its course, eventually leading to death. There has been, and still continues to be excellent interventions in our health care system for palliative care; however people are still dieing with extreme suffering. Palliative sedation is a way to help these people die in a more comfortable way. If a patient is not capable of making their own decisions and has no advanced directives, a health care surrogate can make the decision to introduce palliative sedation based on what he or she thinks the patient may have wanted. There is much to consider when discussing palliative sedation, but if a patient has a terminal illness, has extreme suffering, and no other methods to relieve either physical, emotional, or spiritual pain are working, why not do something that will ultimately put an end to this suffering?
Suffering is subjective, and many people seem to forget about the emotional factors that arise when death is imminent. A dieing patient may have extreme anxiety about leaving behind loved ones, unfinished business, or many other various factors that create extreme anxiety while dieing. Why should these feelings be any less important than physical pain, difficulty breathing, or nausea? It's unfortunate that some physicians feel emotional difficulties are not an appropriate reason to use palliative sedation. Why not do the most possible to create the most comfort? If palliative sedation is the only thing left to try then what else is there left to loose?
Palliative sedation also comes down to autonomy; in that the patient has the right to make his or her own decisions regarding the care they receive. What makes this difficult is that clinicians are not obligated to provide care that violates his or her values and morals. On the other hand, clinicians need to provide care that benefits and promotes the patients well-being. If they refuse to use palliative sedation and nothing else is providing relief from suffering, are they promoting the well-being of that patient? They are obligated to do good and prevent the patient from harm, but what is causing harm is subjective and many clinicians have an issue with making decisions based on subjective information. Our health care system has always said that pain is whatever the patient says it is, so why should palliative sedation fall into different circumstances?
Palliative sedation has recently begun to be used more frequently. Patients are finally dieing comfortably either in their own homes or the hospital setting. Many people have thought of palliative sedation as being the same as physician assisted suicide; I just wanted to point out that there is a difference. Palliative sedation is not using a medication that will immediately end a life; it is putting a person in a state of mind so that they are unaware of their extreme suffering. It is not helping to "fix" the disease or illness, but promoting comfort so the patient can be free of pain and die peacefully. Isn't that all of our hopes, to die peacefully? When a terminally ill patient is at the end of life, palliative sedation is a good alternative to other medications and treatments that are not relieving pain and suffering that come with death.
Friday, December 01, 2006
Palliative sedation is used done with the intent to relieve subjective and objective symptoms. Objective symptoms are those which we can see, such as crying or a pain rating of 10/10. Subjective symptoms we can not see, we can only believe what the patient is telling us. Emotional suffering is often missed because physicians have a hard time sedating a patient based merely on what they are telling you. People remain in anguish due to physicians personal struggle of knowing who is really suffering from those who just want to be sedated as an escape or to hasten their death. As a nurse and as a family member it is really important to advocate for the person who is suffering. We are the ones who know the people best and are able to validate the patients emotional suffering.
Nurses can struggle with palliative sedation because it can hasten death. The reason palliative sedation is ethically ok is due to the intent one has while administering it. The nurse must remember their intension is to promote comfort, but with that death may occur. In order for nurses to continue on and maintain their own stability, they have to remember someone always has to give the last dose of a drug, and they need to remember the good they did for the patient. If a patient dies shortly after a dose of medication you gave, you did not kill them, you simply gave the last dose and the person died because they were ready for one reason or another. Nurses who maintain this sedation for patients are relieving them of suffering and unbearable pain. Doing this for them is not only what the patient wants, but it also restores quality into their life.
Families need to understand the same things that nurses do. They need to know the intention is to relieve pain, which can not be relieved by any other method. Families should be comforted by knowing palliative sedation is freeing the patient of pain.
With this bit of information on palliative sedation, I hope people are more aware and have a better understanding of what it is and how it is useful to patients. This knowledge should be used to free caregivers of the burden they may feel from administering it. This should also free family members of any burden they may feel by choosing to have someone close to them sedated. No one wants to suffer and thanks to palliative sedation no one has to.
Women bear a disproportionate share of the burden of this disease. According to UN figures, more adult women than ever before are now living with HIV. The 17.7 million women living with HIV in 2006 represent an increase of over one million compared with 2004. These numbers don't account for uninfected women who are the primary caregivers for loved ones with AIDS: their lives, too, are deeply affected by the disease.
This article in today's San Francisco Chronicle describes a Bay Area response to the "epidemic" (CDC's term) of HIV/AIDS in the African American community.
Here are resources and info about women and HIV/AIDS:
UNIFEM's resources on gender and AIDS
The Global Coalition on Women and AIDS (UNAIDS)
The Centers for Disease Control
AVERT, an international AIDS charity