World War Z, billed as "an oral history of the Zombie Wars," is a novel by Max Brooks that purports to tell the history of the global battle against the zombie horde. There are of course a number of horror movies along these lines--among them the gorefest 28 Days Later and its equally horrifying sequel, 28 Weeks Later--and a film version of WWZ is supposedly in the works.
The plan credited in WWZ with saving humanity involves the sacrifice of isolated communities: these unfortunates are left behind, as a distraction for the swarm of zombies, while the rest of the population flees. Once the communities have been completely "zombified," the army moves in mows them down. It's not an especially realistic scenario--or at least, one hopes not! But it does raise some interesting questions about what kinds of measures can, or should, be taken in the case of public health emergencies, and whether we all become utilitarians under such circumstances.
Camus' The Plague is, of course, the classic. Geraldine Brooks' Year of Wonders is also very good. And I just picked up a copy of The Last Town on Earth by Thomas Mullen, which is another quarantine story, this one set here in the Pacific Northwest. You'll probably get a review of it here one of these days ... when I have time for leisure reading again!